--- title: Cisco Secure Email  description: "Cisco Secure Email Appliance is a virtual, all-in-one appliance that provides protection against spam, malware, viruses, and other inbound and outbound email threats and annoyances.\n\nTogether, SIRP and Cisco Secure Email deliver advanced email security. SIRP’s integration with Cisco Secure Email allows security teams to execute response actions right from SIRP." --- [Skip to content](https://content.sirp.io/knowledge-base/cisco-secure-email-help-center-sirp#main-content) English Show submenu for translations [Customer portal](https://content.sirp.io/customer-portal?hsLang=en) [![SIRP-Logo-4c-KO](https://content.sirp.io/hs-fs/hubfs/SIRP-Logo-4c-KO.png?width=200&height=90&name=SIRP-Logo-4c-KO.png)](https://sirp.io/) Open main navigation Close main navigation - English Show submenu for translations - [Customer portal](https://content.sirp.io/customer-portal) - [Contact us](https://content.sirp.io/customer-portal/new) [Contact us](https://content.sirp.io/customer-portal/new?hsLang=en) What would you like to automate today? - There are no suggestions because the search field is empty. 1. [SIRP Help Center](https://content.sirp.io/knowledge-base?hsLang=en) 2. [Integration Guide](https://content.sirp.io/knowledge-base/integration-guide?hsLang=en) # Cisco Secure Email ### About Cisco Secure Email Cisco Secure Email Appliance is a virtual, all-in-one appliance that provides protection against spam, malware, viruses, and other inbound and outbound email threats and annoyances. Together, SIRP and Cisco Secure Email deliver advanced email security. SIRP’s integration with Cisco Secure Email allows security teams to execute response actions right from SIRP. ### Supported Actions SIRP’s Cisco Secure Email integration app allows you to execute the following actions: | **S.no** | **Action** | **Description** | | --- | --- | --- | | 1 | Add recipient to blocklist | Add recipient's email address to the blocklist | | 2 | Add recipient to safelist | Add recipient email address to the safelist | | 3 | Add sender to blocklist | Add sender's email address to the blocklist | | 4 | Add sender to safelist | Add sender email address to the safelist | | 5 | Release message from quarantine | Release a quarantined message | | 6 | Lookup IP in messages (last 24 hours) | Lookup last 24 hours' email messages against the given IP address | | 7 | Lookup recipient messages (last 24 hours) | Lookup last 24 hours' email messages against the given recipient's email address | | 8 | Lookup sender messages (last 24 hours) | Lookup last 24 hours' email messages against the given sender's email address | | 9 | Lookup subject messages (last 24 hours) | Lookup last 24 hours' email messages with the given IP address | | 10 | Lookup domain messages (last 24 hours) | Lookup last 24 hours' email messages against the given domain | | 11 | Lookup hash messages (last 24 hours) | Lookup last 24 hours' email messages against the given hash | ### Enable and Configure Cisco Secure Email ### Enabling AsyncOS API **Before You Begin** Make sure that you are authorized to access the IP Interfaces page on the web interface or the `interfaceconfig` command on CLI. Only administrators, email administrators, cloud administrators, and operators are authorized. ### Procedure - Log in to the web interface. - Choose Network \> IP Interfaces. Edit the Management interface.   ``` Note: You can enable AsyncOS API on any IP interface. However, Cisco recommends that you enable AsyncOS API on the Management interface. ``` ``` You must not enable APIs on multiple management interfaces. ``` - Under the AsyncOS API (Monitoring) section, depending on your requirements, select HTTP, HTTPS, or both and the ports to use. ``` Note: AsyncOS API communicates using HTTP / 1.1.If you have selected HTTPS and you want to use your own certificate for secure communication, see Securely Communicating with AsyncOS API. ``` - Submit and commit your changes. ### Create a new user on the Cisco Secure Email 1. Open your Cisco SE instance. 2. In the **Settings** tab from the dashboard, go to **Users.** 3. Create a **New user** and assign a name to them. 4. Also, assign a minimum **operator** role to this new user. **Authorization** The AsyncOS API is a role-based system, the scope of API queries is defined by the role of the user. The email gateway users with the following roles can access the AsyncOS API: - Administrator - Operator - Technician - Read-Only Operator - Guest - URL Filtering Administrator - Email Administrator - Help Desk User ### Enable the Cisco Secure Email app in SIRP 1. First, log in to SIRP, then go to **Apps** from the left navigation bar. 2. Locate the app named **Secure Email.** 3. **Enable** the Email Security app by clicking on the toggle button under the Status Column. [![](https://content.sirp.io/hubfs/Knowledge%20Base%20Import/image-Jul-11-2025-11-55-40-9902-AM.png)](https://downloads.intercomcdn.com/i/o/564579701/a10ecf481e200477cf918ba5/image.png?expires=1752237000&signature=4f5f015170107fb06a5840c47f24223d742a27b30ad47cc6202dd7c2f1947843&req=cSYjE853moFeFb4f3HP0gDt3dXvBSUJ9Pabemv3Tj1geUkxKDMTVBSs7I%2Bsf%0AqpDCJ9ZJLTvRkjrMUg%3D%3D%0A) Once you enable the App, click the **configure** option to integrate SIRP with Cisco ESA. [![](https://content.sirp.io/hubfs/Knowledge%20Base%20Import/image-Jul-11-2025-11-55-48-1161-AM.png)](https://downloads.intercomcdn.com/i/o/564580326/0fe316799e1ee7e34b9320a5/image.png?expires=1752237000&signature=addc90d5d27e68424a7c4f24f4813b0392d6b7390fb20aaa7e93680cf89832db&req=cSYjE8F%2BnoNZFb4f3HP0gCoiNox8U%2Flt7v%2BmM%2Fs%2F0BP%2B7K0O1nUzCV2uCtA2%0A51dhRse%2Bi2DW3kuANA%3D%3D%0A) 1. 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